Inhalt                                                                                                     

 CYTOTOXIC LYMPHOCYTES IN THE ARMAMENTARIUM
OF THE HUMAN HOST PRODUCTS
OF THE EVOLVING UNIVERSAL IMMUNE SYSTEM

 

1. The Innate Immune System

1.1 The Universal Ancestor(s)

1.2 Chemokines and Toll-like Receptors Make
Their Appearance

1.3 Nod

1.4 Viral Evolution

1.5 Interferons and RNAi

1.6 The Ascidian Haemocyte and Its Followers

1.7 Programmed Cell Death

1.8 Bactericidal Substances

1.9 Some Simple Interactions

1.10. Oncogenic Mutations

2. The Adaptive Immune System

2.1 Primordial Adaptive Elements

2.2 Retrotransposons

2.3 Host and Viral Genetic Refinements

2.4 The Placenta

2.5 The Thymus, Bursa of Fabricius, and MALT

2.6 The Host Confronts Mutagenes and Pathogenes
 Attacking Lymphoid Tissues

2.7 T, B, NK, and TREG Cells

2.8 Humoral and Cell-Mediated Immunity

3. Tumor Immunology and Immunotherapy

3.1 Cancer Vaccines

3.2 Natural Lymphoid-Cell Hybridoma Formation
 by Cell Fusions

3.3 Lymphocytes Cytotoxic to Human Tumor Cells

3.4 Adoptive Immunotherapy with Cytotoxic Lymphocytes

4. Autoimmunity and Lymphomagenesis

4.1 Hashimoto's Thyroiditis

4.2 Systemic Lupus Erythematosus

4.3 Autoimmunity and Malignant Thymoma

5. Cytotoxic Lymphocytes against Cellular and
 Viral Infectious Agents

5.1 Complex Eukaryotic Pathogens

5.2 Septic Shock

5.3 Interactions with Intracellular Bacteria

5.4 Anti-Oncoviral Immunity

6. Concise Synopsis 2007-8

6.1 From RNA Nucleotide Concentrates to Syntrophus and
Upward
6.2 Innate Immune Faculties Regulate the Lymphocytes

6.3 Innate and Adaptive Interactions in Infections
 and Malignancies

6.4 Latest Events in Human Cancer Immunology
 and Immunotherapy

Summary

References over 2270 plus single-spaced small type Figures
(Plates) 1 - 12;and Tables 1-14

Acknowledgements